ME/CFS RESEARCH FORUM: 26-27 March 2007
University of Adelaide
Convenor: Alison Hunter Memorial Foundation
Daniel L Peterson MD1, Nancy G Klimas MD2, Judy A Mikovits PhD1 and Annette Whittemore1 1 WPI, Reno NV. 2 University of Miami Miller School of Medicine, Miami FL.
The Whittemore Peterson Institute for Neuro-Immune Disease:
Algorithm for Disease Specific Clinical and Translational Research
The Whittemore Peterson Institute (WPI) will be a comprehensive outpatient medical center and translational research center, dedicated to patient care, basic research, education and drug development for a spectrum of neuro-immune diseases including Chronic Fatigue Syndrome (CFS), atypical multiple sclerosis (MS), fibromyalgia (FM), and Gulf War syndrome. The Institute’s mission is to facilitate and advance patient care, research the patho-physiology and develop therapeutics, diagnostics and prevention strategies for this spectrum of neuro-immune diseases. The WPI currently houses the world’s largest CFS sample repository containing more than 5000 peripheral blood mononuclear cells, serum, plasma, tissue and CSF samples. To support the repository, a fully categorized, searchable database of patient and sample data and a state of the art facility was built and will be moved to the new medical center in 2008. The repository contains a Cyrostorage freezer, a -700C freezer and a bioprocessing lab for sample preparation. Ongoing Research projects include identification of mammalian viruses expressed in subgroups of CFS patients by microarray; Antibody array profiling of CFS subgroups; HHV6 germ line integration and mechanism of HHV6 latency in CFS patients with clonal T cell receptor gamma (TCRG) rearrangements and Mantle Cell Lymphoma (MCL); biomarker discovery for diagnostic applications, drug development. Funding mechanisms include state and Federal appropriation, NIH grants, private donations and the Infrastructure of the WPI will also be discussed.
Alison Hunter Memorial Foundation
PO Box 6132 North Sydney 2059 Australia
Phone/Fax +61 2 9958 6285
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